中医脐疗法治疗慢性肾衰竭的临床探究.pdfVIP

提 要 目的：通过系统的临床研究，观察脐疗法治疗慢性肾衰竭（湿浊热中阻兼脾肾 亏虚证）的疗效、毒副作用和不良反应，评价其安全性及有效性，分析和阐明其治疗 的作用机理，为中医临床治疗慢性肾衰竭提供新的方法与手段。 方法：将 60 例慢性肾衰竭患者随机分成 2 组，治疗组（脐疗组）和对照组（常 规治疗组），对照组予以常规中西医结合治疗 （包括西医常规治疗，中药口服及灌肠）， 治疗组在对照组治疗的基础上辅助以中药脐疗法，疗程8周，观察患者临床症状、实 验室检查等的变化来判定疗效。 结果：临床研究：治疗组临床控制率 16.67％，总有效率 86.67％；对照组临床 控制率6.7％，总有效率 53.33％，两组比较差异有显著性（P0.01）。实验研究表明： 脐疗法在改善脾肾亏虚型慢性肾衰竭的中医各证候方面、降低尿蛋白定量和提高血 浆白蛋白水平方面以及对肌酐清除率、血肌酐、尿素氮的调节有明显疗效，且安全 性好，未发现不良反应。 结论：脐疗法治疗慢性肾衰竭疗效确切，副作用低，其作用机理可能是与脐以筋 膜为主体，通过改善内脏及组织的生理活动和病理变化，达到防病治病的目的有关。 关键词 慢性肾衰竭；脐疗法；疗效及副作用；作用机理研究 The Clinical Research Of Chinese Umbilical Treatment On Treating Chronic Renal Failure Speciality: Medicine of TCM Author:LiHaiyan Tutor: Prof. Mi Jie Abstract Objective: This study aims to observe and confirm the curative effect,side effects and untoward effect of Chinese Umbilical Treatment On treating CRF,which is damp turbidity or damp-heat type.And evaluate itssecurity and effectiveness,analysis and clarity its mechanism of action,offer new method and means to TCM clinical. Method: Using prospective randomized method,we divided 60 cases CRF which is damp turbidity or damp-heat type patients meeting the diagnostic criteria into two groups.30 patients were classified into control group who were treated with intergrtive medicine foundation treatment.Another 30 patients were classified into treatment group who were treated with intergrtive Medicine foundation treatment and chinese umbilical treatment. The CRF syndromes were observed. Moreover ，24h proteinuria, ，blood albumin,blood creatinine, creatinine clearance，etc. was measured and compared before and 8 week after starting the treatment. Results:1.