经皮微波凝固治疗恶性肝肿瘤的初步观察 - 放射学实践.pdfVIP

5 2003 118 1 adiol Practice, Jan 2003, Vol 18, No.1 ## 王精兵 冯敢生 梁惠民 吴汉平 = :评价经皮微波凝固治疗( PMCT) 恶性肝肿瘤的近期疗效, 讨其最佳适应证和治疗相关因素: 应用MTC-3-500s 型微波治疗仪,超声或CT 引导下经皮穿刺热凝固, 对44 例肝肿瘤(52 个结节, 直径2.3~ 8.6cm) 进行了 116 次323 个点的治疗每 个点微波输出功率40~ 60W, 作用时间3~ 6min分别观察肿瘤坏死范围大小变化AFP/ CEA 水平肝功能变化及并发症: 治疗后增强CT 或M I 示肿瘤区完全无强化占69. 2% (36/ 52) , 其中直径[ 5cm 34 个;67.3%(35/52) 的病灶明显缩小;32 例(32/ 36) 原发性肝癌AFP 升高者,28 例明显下降, 且8 例降至正常;8 例转移癌 术前CEA 均升高,术后明显下降所有患者术后肝功能轻度损害, 发生自限性腹腔出血3 例, 少量反应性胸水5例腹水 6 例均经内科治疗恢复: 初步结果表明,PMCT 是一种安全有效的治疗方法, 对于直径5cm 以下的肝肿瘤多可完全 灭活, 对于直径5cm 以上者采用分次治疗可使肿瘤明显缩小 = 肝肿瘤; 介入治疗, 微波/ 治疗应用; 凝固性坏死 = 815, 735.7, 730.5 = A = 1000-0313(2003) 01-0052-04 Percutaneous microwave coagulation therapy for malignant hepatic tumor:preliminary study WANG Jingbing, FENG Gansheng, LIANG Huimin, et al.Department of Interventional adiology,Xiehe hospital,Tongji Medical college,Huazhong Science and Technology University,Wuhan 430022 = Abstract Objective:To evaluate the short-term curative effect of percutaneous microwave coagulation therapy (PMCT) for ma- lignant hepatic tumor and to investigate the indications and the associated factorswith the treatment.Methods:44 patients of 52 hepatic tumors measured from 2.3cm to 8. 6cm in the largest diameter,underwent 116times of PMCT with 323 points guided by ultrasonography or CT.Each point was done with microwave export power 40~ 60 watts and working times 3~ 6 minutes.Then observed was the change of the following as the size and necrosis of the tumor,the level of serum AFP/ CEA, liver function and associated complications. Results: After treatment,enhanced CT or M I demonstratednon- enhancement oftumor lesions in 69.2%(36/52) , o