cd4 调节性t细胞的表面分子标记物和作用机制初探医药学论文（The surface molecular markers and mechanisms of cd4 regulatory t cells were first explored in the pharmacological papers）.docVIP

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cd4 调节性t细胞的表面分子标记物和作用机制初探医药学论文（The surface molecular markers and mechanisms of cd4 regulatory t cells were first explored in the pharmacological papers）.doc

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cd4 调节性t细胞的表面分子标记物和作用机制初探医药学论文（The surface molecular markers and mechanisms of cd4 regulatory t cells were first explored in the pharmacological papers）

cd4 调节性t细胞的表面分子标记物和作用机制初探医药学论文（The surface molecular markers and mechanisms of cd4 regulatory t cells were first explored in the pharmacological papers） Surface molecular markers and mechanisms of action in cd4+ regulatory T cells This article source: paper / [Abstract] cd4+cd25+ regulatory T cells derived from the thymus play an important role in peripheral immune tolerance. The surface expression of a variety of molecular markers, including CD25 (IL-2 receptor alpha chain), cytotoxic T lymphocyte associated antigen -4 (CTLA-4), tumor necrosis factor receptor gene family (GITR) and programmed death 1 (PD-1) and forkhead winged helix transcription factor (Foxp3) and membrane molecule. However, these cell surface molecules are characteristic markers of non regulatory T cells and cannot be distinguished from regulatory T cells and activated T cells. The search for appropriate surface markers will be a critical step toward further research into regulatory T cells. This review focuses on the molecular markers and mechanisms of action of cd4+ regulatory T cells in recent years. [Keywords] cd4+ regulatory T cells; molecular markers; Foxp3 Regulatory T cells (regulatory, t, cell, TR) can block the inflammatory response to autoantigens and limit the development of autoimmune diseases. These immune regulatory cells exist in two ways: one is naturally occurring cells in the body, and the other is the cells that are induced by the induction. This review focuses on the molecular markers and mechanisms of action of cd4+ regulatory T cells in recent years. The origin of 1 cd4+ regulatory T cells Cd4+, cd25+, and Tr cells are the more studied subtypes at present, and others are th3 and tr11. Cd4+ cd25+ Tr cells play an important role in autoimmune tolerance, which originates from cd4+cd25-t cells of thymus. In the process of natural selection in the thymus, T cell receptor (TCR) and mhc-li peptide complexes or thymic endothelial cells of low density recursive peripheral is self pe