毕业论文设计：年产1000万片头孢氨苄生产车间工艺设计.doc

本科生毕业论文（设计） PAGE II 年产1000万片头孢氨苄生产车间工艺设计 摘 要 本设计为年产1000万片头孢氨苄片生产车间工艺设计。头孢氨苄片是采用头孢羟氨苄为主要原料配以辅料淀粉、硬脂酸镁、滑石粉压制而成。按照制剂车间工艺设计要求，本文从生产方法、工艺流程、物料衡算、设备工艺设计、主要设备选型、厂址选择、车间组成及设备布置、公用工程用量、两废的处理以及防火安全卫生等方面进行了全面的设计。 该设计成果主要采用的形式为工艺流程示意图1张，工艺流程图1张，物料平衡图1张，设备布置图1张，车间设备布置图1张，厂区平面图1张，劳动组织分配图1张，并编写了详细的数据说明。 关键词：头孢氨苄；片剂；工艺流程；物料衡算 Technical design for annual output of 10 million cephalexin tablet in workshop Abstract This design is for Technical Design of producing 10 million cephalexin tablets in Workshop. Cephalexin tablet uses cefadroxil as the main raw material and with Starch ,Magnesium Stearate, French chalk as the auxiliary material for tableting. According to the technical design requirement of Preparation workshop,this article covers production methods, technical process, material balance, equipment technical design , major equipment selection, site selection, workshop composition, equipment layout, utility consumption, waste treatment, and fire protection ,safety and healthy as the overall design. The main forms of design achievement is(includs) one piece of process flow drawing, one piece of material balance diagram, one piece of equipment layout, one piece of workshop plan, one piece of factory layout, one pieces of labor organization distribution diagram, and compile the detailed data specification. Key word：Cephalexin;Tablet;Technical;Material balance 目 录 TOC \o 1-3 \h \u HYPERLINK \l _Toc260832388 摘要 Ⅰ HYPERLINK \l _Toc260832388 Abstract Ⅱ HYPERLINK \l _Toc260832389 第1章 绪论 1 HYPERLINK \l _Toc260832390 1.1 概述 1 HYPERLINK \l _Toc260832391 1.1.1我国头孢氨苄现状 1 HYPERLINK \l _Toc260832392 1.1.2头孢氨苄前景 1 HYPERLINK \l _Toc260832393 1.1.3药品生产的特殊性及生产设施和设备的重要性和专业性 1 HYPERLINK \l _Toc260832394 1.1.4选定的剂型发展概况 2 HYPERLINK \l _Toc260832395 1.1.5选定的品种的重要性 2 HYPERLINK \l _Toc260832396 1.2工艺流程设计的原则 2 HYPERLINK \l _Toc260832397 1.3 生产方法选择 3 HYPERLINK \l _Toc260832398 1.3.1制粒压片法 3 HYPERLINK \l _Toc260832399 1.3.2粉末直接压片法 4 HYPERLINK \l _Toc260832400 1.3.3半干式颗粒压片法 4 H