止痒润肤凝胶治疗面部皮炎的临床探究.pdfVIP

提 要 目的：观察止痒润肤凝胶治疗面部皮炎的临床疗效，并探讨其作用机理。方法： 将90例面部皮炎患者随机分为止痒润肤凝胶治疗组、复方黄柏液对照组和基质组。 所有患者均予口服玉屏风颗粒，每日3次每次5g，疗程4周，以面部瘙痒及潮红范 围、肿胀程度、丘疹数目、干燥脱屑程度等为观察指标。结果：经4周临床观察显 示，止痒润肤凝胶治疗组愈显率为87.10%，复方黄柏液对照组愈显率为82.76%，基 质组愈显率为23.33%。结论：止痒润肤凝胶治疗面部皮炎作用温和，疗效确切，其 作用机理与抗变态反应、促进损伤皮肤的屏障功能恢复等有关。 关键词 凝胶；面部皮炎；屏障功能 Clinical Studies of Itch Guard and Skin Moist Gel in Treating Facial Dermatitis Specialty：The Surgery of TCM Author ：Zhang Yu Tutor：Prof.Zhou Chun-Ying Abstract Objective: Observe the clinical efficacy of itch guard and skin moist gel in treating facial dermatitis, and explore its function mechanism. Methods: Randomly divide the 90 dermatitis patients into three groups which is itch guard and skin moist gel treating group, compound cortex phellodendri liquid treating group and matrix treating goup. All patients are orally treated with Yupingfeng granules on the condition that the course of treatment is 5g one time and 3 times every day for 4 weeks. Take facial itching and flush range, swelling degree, papule number, xerosis cutis and desquamation degree of skin for observation indexs. Results: Clinical observation after four weeks shows that the more explicit rate in itch guard and skin moist gel treating group is 87.10%, and the others are 82.76% and 23.33% in compound cortex phellodendri liquid treating group and matrix treating goup. Conclusion: Itch guard and skin moist gel has mild and definite effects on treating facial dermatitis. Its function mechanism is associated with anti-allergic reaction and promoting the recovery of barrier function within the damaged skin. Key words gel; facial dermatitis; barrier function