清热燥湿法对治疗偏头痛患者疗效观察和脑血流动力学变化所起作用的研究.pdfVIP

提 要 目的：为了动态观察偏头痛患者实验组与对照组的的脑血流动力学(TCD)的变 化结果，并进行差异性评价，以探讨症状的好转程度(即头痛指数)与脑血流动力学 变化的相关性。方法：选取符合标准的病例 80 例，随机分为治疗组和对照组各 40 例，并选取同期健康者 80 例。病例组与对照组均检测 TCD。治疗组予头风汤，水煎 服日一剂。对照组予西比灵，每次 10mg 口服，睡前一次。两组均治疗 2 月后通过观 察统计，对比治疗前后临床症状、TCD 报告、头痛指数的变化。结果：临床疗效治 疗组总有效率为 97.5%，显效率为 72.5%；对照组总有效率为 95.0%，显效率为 45.0%。 — — 治疗组优于对照组（R治疗＝0.4003，R对照＝0.6329）；治疗组 TCD 结果改善优于对 照组，头痛指数明显改善。结论：以清热燥湿立法之头风汤可明显改善偏头痛患者 症状，并能明显降低头痛指数，可使患者脑血流动力学变化好转明显，临床疗效、 头痛指数与脑血流动力学变化呈正相关。 关键词 偏头痛；清热燥湿；TCD；疗效对比；差异性与相关性 The research of the clinical observation on Heat-clearing and damp-Drying therapy in the treatment of migraine and the effect on cerebral hemodynamics condition changes Speciality：Neuropathic Author ：Chi Zhaoming Tutor ：Sun Xiqing Abstract Objective: To dynamically observe the difference of cerebral hemodynamics condition changes in treatment group and control group of migraine suffers, the toufeng soap based on Heat-clearing and damp-Drying therapy was given to the treatment group, Flunarizine capsule were given to the control group. By compared the difference in effect and cerebral hemodynamics condition changes of two groups, the correlation of the headache index and the cerebral hemodynamics condition changes was observed, which is used to characterized the ameliorated symptom of migraine. Methods: 80 cases according with diagnostic criteria for migraine were randomly divided into the treatment group and control group, so each group has 40 cases, as the same time ，80 healthy cases were chosen to contrast the case group. all the group need to be detected by Traseranial Doppler Ultra sound (TCD).the toufeng soap was given to the treatment group. The toufeng soap was de