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围生期缺血性脑卒中 母得志 作者单位：四川大学华西第二医院儿科 (成都，610041) Email：dezhimu@ 围生期脑卒中是指从孕28周到生后1周内，各种原因导致脑血管狭窄、闭塞或破裂，而造成局部脑血流循环障碍性疾病 ADDIN EN.CITE EndNoteCiteAuthorRaju/AuthorYear2007/YearRecNum251/RecNumrecordrec-number251/rec-numberforeign-keyskey app=EN db-id=spvev2fei0tpacerppypddax059rda0rdts5251/key/foreign-keysref-type name=Journal Article17/ref-typecontributorsauthorsauthorRaju, T. N./authorauthorNelson, K. B./authorauthorFerriero, D./authorauthorLynch, J. K./author/authors/contributorsauth-addressNational Institute of Child Health and Human Development, Bethesda, MD 20892, USA. rajut@/auth-addresstitlestitleIschemic perinatal stroke: summary of a workshop sponsored by the National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and Stroke/titlesecondary-titlePediatrics/secondary-title/titlesperiodicalfull-titlePediatrics/full-title/periodicalpages609-16/pagesvolume120/volumenumber3/numberedition2007/09/04/editionkeywordskeywordFemale/keywordkeywordFetal Diseases/diagnosis/keywordkeywordHumans/keywordkeywordInfant, Newborn/keywordkeywordInfant, Premature/keywordkeywordInfant, Premature, Diseases/diagnosis/keywordkeywordNational Institutes of Health (U.S.)/keywordkeywordPregnancy/keywordkeywordRisk Factors/keywordkeywordStroke/classification/ complications/ diagnosis/keywordkeywordTerminology as Topic/keywordkeywordUnited States/keyword/keywordsdatesyear2007/yearpub-datesdateSep/date/pub-dates/datesisbn1098-4275 (Electronic)#xD;0031-4005 (Linking)/isbnaccession-nuaccession-numurls/urlselectronic-resource-num120/3/609 [pii]#xD;10.1542/peds.2007-0336 [doi]/electronic-resource-numremote-database-providerNlm/remote-database-providerlanguageeng/language/record/Cite/EndNote[1]。围生期脑卒中分为缺血性脑卒中，出血性脑卒中和脑静脉窦血栓形成。其中，以缺血性脑卒中最常见，是脑瘫和惊厥的主要病因之一，给患者家庭和社会带来沉重的经济负担 ADDIN EN.CITE ADDIN EN.CITE.DATA [2-3]。尽管随着神经影像学技术的进步，儿科医师对围生期缺血性脑卒中诊断水平提高，但是，由于围生期缺血性脑卒中病因复杂，临床缺少特异表现，也无有效的预防和治疗措施。因此，受到了国外围生期专家的广泛关注，本文将探讨围生期缺血性脑卒中，尤其在早产儿中发病的危险因素、临床表现和影