口腔病理学0201（Oral pathology 0201）.docVIP

口腔病理学0201（Oral pathology 0201） Twelfth unit oral mucosal disease Section 1 basic pathological changes The second section is about the pathology of oral mucosa diseases Outline requirements: 1. basic pathological changes 1) hyperkeratosis and hyperkeratosis 2) epithelial dysplasia 3) vacuolar degeneration and liquefaction of basal cells 4) blister 5) papules 6) erosions and ulcers 2.. Common pathology of oral mucosal diseases (1) oral leukoplakia (2) oral lichen planus (3) chronic discoid lupus erythematosus Section 1 basic pathological changes Hyperkeratosis and hyperkeratosis Excessive hyperkeratosis: also known as hyperkeratosis, refers to the mucosa or skin hyperkeratosis thickening. In the mouth mucous membrane, refers to the normal condition, has the keratinization region, the keratinization layer thickening or the normal when the non keratosis region appears the keratinization. There are two kinds: 1.: excessive orthokeratinized cells is unclear, the nucleolus and the formation of keratosis, accompanied by granular layer thickening and keratohyalinegranules anomalies; 2. excessive hyperkeratosis: residual nuclei are seen in thickened keratinized layer, but the granule layer is not obvious. (two) hyperkeratosis: also called keratosis, refers to the epithelial spinous layer or basal layer of individual or group of cell keratinization. There are two cases: 1. benign hyperkeratosis, mostly in the highly proliferative epithelial nail process, and well differentiated cells; 2. malignant hyperkeratosis, sometimes visible nuclei, cell morphology atypia, seen in severe dysplasia, carcinoma in situ and squamous cell carcinoma. Two 、 epithelial dysplasia Atypia: alteration of individual cells associated with precancerous lesions Epithelial dysplasia: epithelial general disorder Epithelial dysplasia may occur following changes (understood): The epithelial basal cell polarity disappeared; the emergence of more than one layer of basaloid cells; the karyoplasmic ratio increa