Alpha Amylase Inhibition Activity of Some Plants …（α-淀粉酶抑制活性的植物u2026）.pdfVIP

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Alpha Amylase Inhibition Activity of Some Plants …（α-淀粉酶抑制活性的植物u2026）.pdf

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Alpha Amylase Inhibition Activity of Some Plants …（α-淀粉酶抑制活性的植物u2026）

European Journal of Biological Sciences 7 (1): 26-31, 2015 ISSN 2079-2085 © IDOSI Publications, 2015 DOI: 10.5829/idosi.ejbs.2015.7.01.91127 Alpha Amylase Inhibition Activity of Some Plants Extract of Teucrium Species 1Zohre Mirzaalian Dastjerdi, 2 Foroogh Namjoyan and Mohamad 3 Ebrahim Azemi 1Graduate of Pharmacy, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 2Marine Pharmaceutical Research Center, Pharmacognosy Department, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 3Department of Pharmacognosy, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Abstract: Diabetes Mellitus is a metabolic disorder characterized by high blood glucose level caused due to deficiency of insulin secretion or insulin action. The inhibition of carbohydrate hydrolyzing enzymes such as a-amylase can be an important strategy in the postprandial blood glucose level in patients with type II diabetes Plants contains different chemical constituents with potential for inhibition of -amylase and hence maybe used as therapeutic. three plants of Teucrium species of were tested for -amylase inhibition. Different concentrations of extracts were incubated with enzyme substrate solution and the activity of enzyme was measured. Also Acarbose was used as the standard inhibitor. Three plant extracts showed inhibition of -amylase, The -amylase inhibitory activities of extracts are T. poliumT. oliverianumT. Orientale. The IC50 value of Hydroalcoholic extract of T. polium was 3.63 mg/ml. The IC50 value of T. oliverianum and T. Orientale