Biologically active polysaccharides from medicinal plants of the Far East：（生物活性多糖的药用植物）.pdfVIP

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Biologically active polysaccharides from medicinal plants of the Far East：（生物活性多糖的药用植物）.pdf

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ChemistryofNatural Compounds, VoL 33, No. 2, 1997 B I O L O G I C A L L Y A C T I V E P O L Y S A C C H A R I D E S F R O M M E D I C I N A L P L A N T S O F T H E F A R E A S T S. V. Tomshich, N. A. Komandrova, E. N. I~almykova, UDC 577.114:633.88.571.6:615.277 N. G. Prokofeva, V. A. Momontova, P. G. Gorovoi, and Yu. S. Ovodov In a searchfor biologically active polysaccharides, we have investigated ten species ofplants from sixfamilies of theflora of the Far East. By successive extractions with water and solutions of ammonium oxalate and of sodium hydroxide we have isolatedpolysaccharides from the roots and epigeal parts and have determined their qualitative and quantitative monosaccharide compositions. Thepolysaccharides obtained have been studiedfor immunostimulating, antitumoral, and antiviral activities. Plant polysaccharides are attracting ever-increasing attention as an important class of biopolymers possessing a broad spectrum of biological action. Antitumoral, immunostimulating, hypoglycemic, anticomplement, antiinflammatory, anticoagulant, and other types of activities have been found in these compounds [1-4]. The rich and unique flora of the Far East may serve as a source of biologically active polysaccharides. To select the most interesting and promising sources, we have made a comparative study of ten species of plants from six families of the Far Eastern flora: Polgonatum odoratum (Mill.) Druce and Polygonatum stenophyUum Maxim. (Liliaceae), Ampelopsisjaponica (Thunb.) Makino (Vitaceae), Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook, f., Glehnia littoralis F. Sehmidt, Heracleum moellendorffii Hance and Sap