对虾抗病毒免疫研究现状.PDF

第23卷第12期 生命科学 Vol. 23, No. 12 2011年12月 Chinese Bulletin of Life Sciences Dec., 2011 文章编号：1004-0374(2011) 12-1296-04 对虾抗病毒免疫研究现状 1 2 1* 高　溳 ，金春英，王　蔚 1 361005 2 361021 ( 国家海洋局第三海洋研究所，厦门 ； 华侨大学化工学院，厦门 ) 摘　要：白斑综合征病毒(white spot syndrome virus, WSSV) ，是对虾养殖中主要的致病病毒，在全球范围 内引起急性感染和致死反应，带来巨大的经济损失。之前的研究主要集中在对虾的先天免疫反应上，在抗 病毒反应方面的尚所知有限。总结了近年来对虾抗病毒免疫研究取得的主要成果，概括了病毒侵染对虾后 分子水平上的改变，旨在为更加有效的预防和治疗白斑综合症提供参考。 关键词：对虾 ；白斑综合征；抗病毒免疫 中图分类号：Q959.223+ .63; Q939.4; Q939.91 文献标志码 ：A Advances on antiviral immunity in shrimp 1 2 1* GAO Yun , JIN Chun-Ying , WANG Wei (1 Third Institute of Oceanography, State Oceanic Administration Xiamen 361005, China; 2 Institute of Chemical Technology, Hua Qiao UniversityXiamen 361021, China) Abstract: White spot syndrome virus (WSSV) is one of the most devastating pathogens in shrimp aquaculture, which has spread worldwide with a high infection and mortality rate and caused tremendous economic loss. Earlier studies on the immunity of shrimp have mainly focused on innate immunity and as a consequence little is known about the antiviral responses. The objective of this review is to update rescent knowledge about the antiviral responses in shrimp, especially shrimp responses to viral pathogens at the molecular level. We aim to provide a promising strategy for protection and treatment of the disease. Key words: shrimp; white spot syndrome virus; antiviral immunity 对虾白斑综合征病毒(white spot syndrome virus, 对虾必须利用其先天免疫系统应对不良环境。对虾 WSS