利用参考点压痕量测技术检测活体内骨骼组织之机械性质.PDF

Probing in vivo Mechanical Properties of Bone Tissues by Reference Point Indentation Technique Po-Yu Chen A novel indentation technique which can probe the mechanical properties of bone tissues in vivo is introduced in this paper. The reference point indentation (RPI) instrument consists of a reference probe and a testing probe. By inserting the probes through the skin onto tibia bone, various mechanical properties such as hardness, elastic modulus, maximum indentation distance, indentation distance increase (IDI) can be measured non-invasively. The results showed that IDI were signifi cantly higher in patients who suffered from bone fracture than in controls and can be used to evaluate fracture risk. The technique has a great potential in the medical fi eld and can provide better understanding of the in vivo mechanical properties of bone tissues. (bone mass density)(2) (1) (computerized tomography)(3) (remodeling) 20 101.10 m n 5 1. Mineralized