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Optimal Management of Peripheral Arterial (外周动脉的优化管理)
Ulster Med J 2011;80(1):33-41
Grand Rounds
Optimal Management of Peripheral Arterial Disease
for the Non-Specialist
12 1 1 1 1
ME O’Donnell , JA Reid , LL Lau , RJ Hannon , B Lee
Accepted 20 October 2010
ABSTRACT Peripheral arterial disease (PAD) now affects approximately 20% of adults older than 55 years to an estimated
total of 27 million people in the Western World. The aim of this paper is to describe the medical management of PAD for the
non-vascular specialist, particularly general practitioners, where PAD has now been included in the Northern Ireland Department
of Health’s Primary Care Service Framework (Directed Enhanced Service).
KEYWORDS Peripheral Arterial Disease, Epidemiology, Investigation, Treatment.
DEFINITION two-fold male predominance (1.8% for women and 3.6%
for men). However, the Edinburgh Artery Study failed to
Peripheral arterial disease (PAD) is defined by the presence
demonstrate any significant difference in PAD between men
of significant narrowing of arteries distal to the arch of the and women9. The risk of PAD increases two- to three-fold
aorta, most often due to atherosclerosis1, 2. Clinically, PAD 10
for every 10 year increase in age after 40 years . More
most commonly affects the lower limbs as a consequence of
arterial narrowing distal to the aortic bifurcation1, 2. recently, IC was reported to be more common in men, whereas
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