Photon Counting Sensors for Medical and （光子计数为医疗和传感器）.pdfVIP

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Photon Counting Sensors for Medical and （光子计数为医疗和传感器）.pdf

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Photon Counting Sensors for Medical and （光子计数为医疗和传感器）

SPECIAL: BIOPHOTONICS Optical Detectors Photon Counting Sensors for Medical and Biophotonic Applications ULTRA SENSITIVE DETECTORS WITH SILICON PHOTON COUNTING SENSORS . n o i t u b Biophotonic analysis methods are often based upon the measurement of small light quanti- i r t s i ties. A new generation of photon counters is not only cheap and easy to integrate but d c i propagate in addition the development and miniaturisation of powerfull measuring devices. n o r t c e l e r STEPHEN BELLIS of-care and point-of-use instrumentation voltages, complicated drive electronics) o f t CARL JACKSON customised for the individual within the re- they have only penetrated a small portion o N ANDREAS KÖNIG quired detection environment. These deve- of the total market for biological photon . s lopments centre on the use of novel low counting. Intensified CCD (ICCD) and the e t i Low light sensing is an established light sensors that can be implemented eit- electron-multiplying CCD (EMCCD) have s t e field that makes many of the biome- her as single high-speed detectors or as emerged in the past decade, however, these n a Vdical discoveries of today possible. large area PMT replacements or within a devices are expensive and require extensive r t n The combination of fluorescent probes, photon counting array in emerging in-vivo cooling. Also with new emphasis by manu- i r o high speed lasers and photon counting de- detector systems.