仙龙定痛饮治疗骨转移癌痛的临床观察.pdf

·2 7 4 。 WORLD CHINESE MEDICINE September . 2007 , Vol. 2 ,No. 5 。Im 床 月开究 · 仙龙定痛饮 治疗 骨转移癌痛 的临床 观察 刘译鸿* 徐 凯中 陈达灿 申 ( * 广东省中医院，广东省广州市大德路 II I 号，510 120 摘要 目的:通过随机对照研究，探讨仙龙定痛饮治疗骨转移癌疼痛的临床疗效。方法:选择60 例各类骨转移癌患者随机分为 治疗组30 例和对照组30 例。治疗组予仙龙定痛饮 + 美施康定，对照组单纯予美施康定。两组治疗疼痛缓解有效率达50% ( CR +PR 时，观察比较两组治疗前后生活质量变化( PS评分、FLIC 量表 、不良反应、美施康定的使用剂量变化。结果:两组治 疗后FLIC 量表评分较治疗前均有显著改善( 尸0. 0 1 ，但治疗组较对照组提高更明显，具有显著性差异( 尸 0. 01 ; 治疗组 胃 肠反应及神经系统反应有所好转，与对照组比较具有差异性( 尸 0. 05 ; 两组美施康定用量及最大量比较有明显差异性。结 论:仙龙定痛饮时骨转移癌痛患者具有确切疗效，该药能改善患者癌痛症状，提高患者的生存质量 ，减少吗啡类止痛药的临床使 用剂量 ，从而相时减少其毒副反应，且未发生毒、副作用。 关键词 骨转移癌疼痛/ 中医药疗法; @ 仙龙定痛饮 Clinical Obser vation of Xianlong Dingtong Yin on Osseous Metastasis Caused Pain Liu Yihong, Xu Kai ，Chen Dacan ( Guangdong Hospital of Chinese Medicine, Guangzhou ,5 10120 Abstract Obj ective :to observe the clinical curative effect of Xianlong Dingtong Yin on osseous metastasis caused pain using random control studies. Methods :60 cases with Osseous Metastasis were randomly divided to treatment group ( 30 cases to be treated with the drink and Morphine sulfate and control group ( 30 cases to be treated with Morphine sulfate alone. When effective rates ( CR + PR re ached 50% ，changes of quality of life ( PS rating, FLIC ，side eff ects, dosage of Morphine sulfate were compared before and after treatment. Results :both groups signiif cantly improved in FLIC ( P 0. 01 ，while the diff ere nce between them was significant ( P 0. 0 1 ; treatment group was signiif cantly better than control group in gastrointestinal reaction and nervous system( P 0. 05 ; conven- tional and maximum dosage of Morphine sulfate were signiif cantly different . Conclusion :the drink has signiif cant curative eff ects for osse- ous metas tasis caused pain , improving quality of life ,