七氟醚及异氟醚吸入麻醉用于全子宫切除术麻醉效果观察.doc

七氟醚及异氟醚吸入麻醉用于全子宫切除术麻醉效果观察[摘要] 目的 观察并比较七氟醚和异氟醚吸入麻醉用于全子宫切除术的麻醉效果。方法 120例行择期全子宫切除术的女性患者随机分为七氟醚和异氟醚各60例，麻醉诱导后分别吸入七氟醚和异氟醚麻醉。观察并记录诱导前（T0）、插管5min后（T1）、切皮（T2）、睁眼时（T3）和拔管前（T4）患者的HR、MAP和SpO2。观察并记录患者的睁眼时间和拔管时间。结果 七氟醚和异氟醚组T0、T1、T2、T3和T4时刻的HR、MAP和SpO2比较，差异均无统计学意义（P＞0.05）。七氟醚和异氟醚组的睁眼时间分别为（7.2±2.5）min和（12.6±3.2）min，差异具有统计学意义（P＜0.05）；两组拔管时间分别为（8.7±2.8）min和（14.3±3.6）min，差异具有统计学意义（P＜0.05）。结论 七氟醚和异氟醚吸入麻醉用于全子宫切除术麻醉，对患者的生命体征均无明显影响，但七氟醚组术后苏醒时间更快。 [关键词] 七氟醚；异氟醚；吸入麻醉；全子宫切除术 [中图分类号] R614[文献标识码] B [文章编号] 1673-9701（2011）21-132-02 Effects of Sevoflurane and Isoflurane Inhaled Anesthesia on Total Hysterectomy XU Zhefeng Department of Anesthesiology, Zhejiang Yongkang First People’s Hospital, Yongkang 321300, China [Abstract] Objective To observe and compare the effect of sevoflurane and isoflurane inhaled anesthesia on total hysterectomy. Methods One hundred twenty cases of patients treated with total hysterectomy were randomly divided into sevoflurane group（n＝60）and isoflurane group（n＝60）. After the induction of anesthesia they were inhaled sevoflurane and isoflurane for general anesthesia, respectively. The HR, MAP and SpO2 were evaluated of the two groups at the moment at before induction（T0）, 5 min after intubation （T1）, cutting skin（T2）, eye open （T3） and before decannulation （T4）. Results The HR, MAP and SpO2 produced no difference between the two groups at T0, T1, T2, T3 and T4. The time of eye open in sevoflurane group was （7.2±2.5） min, shorter than （12.6±3.2） min of isoflurane group（P＜0.05）; The time of decannulation was （8.7±2.8） min in sevoflurane group, shorter than （14.3±3.6）min of isoflurane group （P＜0.05）. Conclusion Sevoflurane and isoflurane inhaled anesthesia both produce no influence on vital signs, but the cases in sevoflurane group wake sooner after total hysterectomy. [Key words] Sevoflurane; Isoflurane; Inhaled anesthesia; Total hysterectomy 全子宫切除术是妇科常见手术，是宫颈癌、子宫肌瘤、子宫内膜异位最常见的手术治疗方法。随着手术技术的发展，手术时间相应缩短，这就要求麻醉平稳、恢复快。笔者分别用七氟醚和异氟醚吸入麻醉用于全子宫切除术，以探讨两种药物的麻