妊娠外阴尖锐湿疣激光术后外用中药颗粒剂临床研究.doc

妊娠外阴尖锐湿疣激光术后外用中药颗粒剂临床研究[摘要] 目的：探讨妊娠外阴尖锐湿疣保胎者激光术后外用中药颗粒剂的临床疗效及预后。方法：对110例妊娠合并外阴尖锐湿疣保胎者CO2激光治疗后，分治疗组55例配合中药颗粒剂外洗，对照组55例配合PP粉外洗，比较两组的疗效。结果：治疗组比对照组的尖锐湿疣复发率低，术后反应小，创面愈合快，疗效好，副作用小，有利于继续妊娠及正常分娩。结论：妊娠合并外阴尖锐湿疣者，用CO2激光配合中药颗粒剂外洗，使用安全，治疗效果好，操作方便，可以继续保留胎儿，对正常分娩无影响。 [关键词] 尖锐湿疣；妊娠；治疗；预后 [中图分类号] R711 [文献标识码]A [文章编号]1673-7210（2008）06（b）-068-02 Clinical analysis of topical Chinese drug granules after laser operation on pregnancy with vulval condyloma acuminatum YANG Zhao-lin1, LIN Huan-er2 (1.Department of Gynaecology and Obstetrics, Fuyong Hospital, Shenzhen518103,China;2. Department of Dermatology, Changping Hospital, Dongguan523573,China) [Abstract] Objective:To assess the clinical effect and prognosis of topical Chinese drug granules after laser operation on pregnancy with vulval condyloma acuminatum. Methods:After carbon dioxide(CO2) laser operation, 110 cases of pregnancy with vulval condyloma acuminatum were divided into two groups randomly: the treatment group(55 cases) were treated with topical Chinese drug granules and the control group(55 cases) were treated with topical PP powder. The clinical effects of the two groups were compared.Results: Compared with the control group, the treatment group had lower relapse rate, minor response after operation, lower wound healing time, better clinical effect and lower adverse reaction. Conclusion:Topical Chinese drug granules after laser operation is a safe and effective method for pregnancy with vulval condyloma acuminatum. [Key words] Condyloma acuminatum; Pregnancy; Treatment; Prognosis 近年来，尖锐湿疣(CA)发病有上升趋势，妊娠患尖锐湿疣同样有上升趋势。专家认为，妊娠CA应尽早将之去除，可减少复发及继续增多的机会，同时可防止病毒传播给胎儿，妊娠期发生CA常病情严重，易复发，控制较困难(一般2个月以上)，我们采用CO2激光配合中药颗粒剂外洗治疗妊娠外阴尖锐湿疣患者55例，应用方便，疗效满意，现分析如下： 1 资料与方法 1.1一般资料 2003年12月～2007年12月，在我院和东莞常平医院诊治的妊娠外阴尖锐湿疣患者110例，年龄20～36岁，平均26.2岁；孕周为7～30周，平均15.8周；发现外阴赘生物的时间为1～12周，平均5.1周。本组病例皮损大多开始为多发性，损害迅速增多、增大，疣体组织质软，血管丰富且容易形成弥漫性损害或较大湿疣损害，临床症状为白带增多，妇科检查外阴及肛周等部位有刺状、鸡冠状或菜花状赘生物，表面灰白色或粉红色，粗糙，大小由芝麻大至直径8 cm不等，呈散在或片状生长，血尿及肝、肾功能