急性呼吸道感染患儿C反应蛋白-白细胞计数-免疫球蛋白检测意义.docVIP

急性呼吸道感染患儿C反应蛋白\白细胞计数\免疫球蛋白检测意义[摘要] 目的 探讨C反应蛋白（CRP）、白细胞计数及免疫球蛋白（Ig）检测对急性呼吸道感染患儿的诊断、鉴别诊断价值。方法 将我院收治的呼吸道感染急性期患儿80例分为细菌感染组、病毒感染组，选同期80例健康儿童作为对照组，比较三组患儿的白细胞计数、C反应蛋白（CRP）及免疫球蛋白（Ig）含量。结果 治疗前细菌组和病毒组的C反应蛋白、白细胞计数、免疫球蛋白含量与对照组比较，差异均有统计学意义。治疗后CRP有明显下降。结论 三种方法联合应用可更准确判断组织炎症及机体受损的程度，有助于及时、准确地反映患者的病情和治疗效果，值得临床推广应用。 [关键词] 急性呼吸道感染；C反应蛋白；白细胞计数；免疫球蛋白 [中图分类号] R725.6[文献标识码] B [文章编号] 1673-9701（2011）20-115-02 Significance of C-Reactive Protein， White Blood Cell Count and Immunoglobulin Detection in Children with Acute Respiratory Infection SUN Guoxian Department of Paediatrics， Shaoxing People’s Hospital， Shaoxing 312000， China [Abstract] Objective To explore the diagnosis and differential diagnosis value of C-reactive protein （CRP）， white blood cell count and immunoglobulin （Ig） detection in children with acute respiratory infection. Methods 80 cases of children with acute respiratory infections in our hospital were divided into bacterial infection group and viral infection group， and 80 cases of healthy children in the same period were selected as the control group. The white blood cell count， CRP and Ig contents of children in three groups were compared. Results CRP， white blood cell count and Ig of bacterial infection group and viral infection group had significant differences when compared with those of control group before treatment， and CRP decreased significantly after treatment. Conclusion Combined detection of three indicators can determine the body tissue inflammation and the extent of damage more accurately， contribute to timely and accurately reflect the patient’s condition and treatment effect， and be worthy of clinical application. [Key words] Acute respiratory infection； C-reactive protein； White blood cell count； Immunoglobulin 儿童一旦患上细菌感染性疾病则很难用语言表达有何不适的感觉。因此，在儿科采用灵敏、简便、快速的检验方法对患儿的疾病进行诊断是十分必要的。白细胞计数是最常用的方法之一，但不能单从白细胞计数情况判断患儿的病情，还要结合其他指标，比如C反应蛋白（CRP）和免疫球蛋白的检测，它们是患儿被细菌感染或遭受创伤后反应最为敏感的一种急性时相蛋白[1]，虽然其浓度变化对反应疾病的变化是非特异性的，但仍对临床疾病的诊断、鉴别诊断及疗效判定有参考价值。目前，C反应蛋白检