新生儿淋菌性眼炎快速诊断及治疗.doc

新生儿淋菌性眼炎快速诊断及治疗【摘要】目的：探讨一种快速诊断新生儿淋菌性眼炎的方法――TF染色法。方法：先后对25例来门诊和住院的新生儿（均有眼分泌物增多）采集眼分泌物进行涂片，并做TF染色后置显微镜下查找淋球菌，同时追问其家长是否有婚外性行为以及有关卫生情况。结果：有5例诊断为新生儿淋菌性眼炎，与其家长（一方或双方）有婚外性行为相符，并对上述患儿进行了及时治疗，均治愈出院。结论：TF染色法可快速检查新生儿眼分泌物中的淋球菌，同时结合其家长的病史（主要指有婚外性行为）对快速诊断新生儿淋菌眼炎具有较强的实用价值。 【关键词】TF染色法；快速诊断；治疗；淋菌性眼炎 文章编号：1009-5519（2007）19-2866-02 中图分类号：R77 文献标识码：A Fast diagnosis and treatment of gonococcal ophthalmia in newborn YU Qiang (The Maternal and Child Health Hospital of Hongan,Hubei 438400,China) 【Abstract】Objective:To introduce a fast diagnostic way of gonococcal ophthalmia in newborn,ie,TF staining method.Methods:The eye secretion was collected from 25 newborns who were out-and in-patients with much eye secretion and smeared respectively.These smears were stained with TF staining method,and then looked for gonococcus under microscope.The illegimate sexual act of parents and some related sanitations were investigated respectively at the same time.Results:Five of 25 newborns were diagnosed as gonococcal ophthalmia,which agreed with the illegimate sexual act of their parents(unilateral father or mother or both father and mother).The sick newborns with gonococcal ophthalmia were treated in time,and all were cured and discharge.Conclusion:Combined with the related illness of parents(especially illegimate sexual act),the TF staining method could rapidly examine gonococcus in eye secretion of newborn.So it is suggested that the TF staining method possessed a stronger utilized value in the diagnosis of gonococcal ophthalmia in newborn. 【Key words】TF staining method；Fast diagnosis；Treatment；Gonococcal ophthalmia 淋病是最常见的性病之一，在小儿淋病中以新生儿淋菌性眼炎和幼女淋菌性外阴阴道炎较多见，尤其是孕妇感染淋球菌后，增加了母婴传播的机会，可因分娩将产道的淋菌直接传染给所生的新生儿，引起眼炎。表现为眼分泌物增多并呈脓性外观，眼结膜充血、水肿，不易睁眼。由于淋球菌培养时间较长，而用涂片检查，方法简便、有效并有一定的特异性[1]；为探讨一种新的淋菌涂片快速染色方法，特选用了喻强建立的用途广泛的TF染色法[2～5]，先后对25例有眼分泌物增多的新生儿做淋菌染色检查，共检出5例，并结合患儿家长的病史（均有婚外性行为）将5例诊断为新生儿淋菌性眼炎，现予介绍。 1 资料和方法 1.1 临床病例：先后选择25例眼分泌物增多的新生儿，其中门诊就诊16例，住院患儿9例（剖宫产2例，自然分娩7例），其日龄均在3～22天之间。 1.2 染