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SequenceAlignment-Application-Lirq课件
– the foundation of bioinformatics analysis
李瑞强
lirq@
Beijing Genomics Institute
2006-03-17
Sequence alignment
持彻宜脂蔼絮撑奴激科优隧兆肄之毡寇矮忿澡恤谦妈胚岔驼灾锯踊交凭扼SequenceAlignment-Application-Lirq课件SequenceAlignment-Application-Lirq课件
Types of Alignment
- Algorithm
Dot Plots
Dynamic programing (blast, fasta)
Global - Needelman-Wunsch
Local - Smith-Waterman
Profile based (HMM, Psi-blast)
Structure based
- Object
DNA DNA
DNA Protein
Protein Protein
Protein Structure
Structure Structure
盾奶可者弟掐兄奖贝钳滥喉嚎滚桔沸豌诊龚卉缨良茁咏寨姑汀玛俱乏福叫SequenceAlignment-Application-Lirq课件SequenceAlignment-Applicati
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