PPARδ基因+294T-C多态性与代谢综合征的关系探讨.docVIP

　　PPARδ基因+294T/C多态性与代谢综合征的关系探讨 ：王静 童国玉 沈山梅 黄洪 杨东辉 朱大龙 【摘要】 　　目的 研究过氧化物酶体增殖物激活受体（PPAR）δ+294T/C多态性与代谢综合征（MS）的相关性。方法 选取346例南京地区中国人(其中MS组118例，非MS组228例)，用Touch-dopact of peroxisome proliferator-activated receptor δ gene ( PPARδ) single nucleotide polymorphism ( SNP) on metabolic syndrome (MS) in Chinese. Methods The genotypes of PPARδ+294T/C ined by Touch-doetabolic syndrome and 118 patients etabolic syndrome. Phenotype measured ass index (BM I); a glucose level， serum insulin level of blood obtained both at 0，30，60 and 120 minute during oral 75 g glucose tolerance test (OGTT); serum lipid level