1 引言部分存在的问题写的具体，与研究目的存在 - 内科急危重症杂志.doc

586例冠状动脉慢性完全闭塞患者PCI治疗疗效及相关因素分析 赵东晖，范谦1，柳景华1，葛广豪2 （1.首都医科大学附属北京安贞医院，北京市心肺血管疾病研究所 100029；2.上海市奉贤区中心医院 201400） 基金：上海市卫生局青年课题（20134y116） 摘要 目的：评估经皮冠状动脉介入治疗(PCI)对冠状动脉慢性完全闭塞(CTO)患者的治疗效果，并探讨影响介入治疗效果的相关因素。方法：回顾性分析我院心内科近期收治的586例经PCI治疗的CTO患者的临床资料。分析CTO患者行PCI治疗的疗效及相关影响因素。结果：CTO患者PCI的成功率为80%。术中并发症(7.7%)，分别是冠状动脉穿孔8例，心包穿孔及心包压塞5例，支架血栓形成4例，严重心律失常(房扑、房颤、室性心动过速及室颤)22例，手术相关心绞痛6例。影响PCI治疗成功的患者自身因素有年龄(P=0.034),高血压史(P=0.041),糖尿病史(P=0.032),发病至治疗的时间(P=0.008)；病变相关因素有冠脉闭塞部位(P0.05)、冠脉分支迂曲程度(P=0.015)、闭塞血管远端缺如(P=0.044)及合并钙化(P=0.007)。结论：CTO患者进行PCI治疗的效果良好。患者的个人病史、病变特点、及治疗实施是否及时是决定介入治疗成功的关键因素。 关键词：冠状动脉慢性完全闭；介入治疗；治疗效疗 The clinical effect of PCI treatment in chronic total occlusion of coronary artery patients and the factors affecting the success ZHAO Dong-Hui1, FAN Qian1, LIU Jing-Hua1,GE Guang-Hao2 (1.Beijing Anzhen Hospital, Capital Medical University Beijing Institute of cardio vascular disease 100029;2. Fengxian District Central Hospital, Shanghai 201400 ) Abstract Objective: To evaluate the effect of percutaneous coronary intervention (PCI) on coronary chronic total occlusion (CTO) patients, and to explore the influencing factors of interventional therapy. Methods: The clinical data of 586 cases with CTO who accepted PCI in the department of Cardiology of our hospital were retrospectively analysed. The effects and influencing factors were compared and analysed. Results: The success rate of PCI was 80%. Intraoperative complications were mild (7.7%), including 8 cases of coronary artery perforation during operation, 5 cases of pericardium perforation and cardiac tamponade, 4 cases of stent thrombosis, 22 cases of severe arrhythmia (atrial flutter, atrial fibrillation, ventricular tachycardia and ventricular fibrillation Heartbeat), and 6 cases of operation related angina. The patients’ own factors which influenced the treatment were age (P=0.034), history of hypertension (P=0.041), history of diabetes mellitus (P=0.032), and the length of time from onset to treatment (P=0.008). The factors relate