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静电纺壳聚糖胶原蛋白复合纳米纤维的细胞相容性.PDF
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Journal of Clinical Rehabilitative Tissue Engineering Research January 1, 2008 Vol.12, No.1
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1 1 1 1 12
Cell biocompatibility of electrospun chitosan/collagen composite nanofibers
1 1 1 1 1,2
Wang Pei-wei , Chen Zong-gang , Wang Hong-sheng , He Chuang-long , Mo Xiu-mei
Abstract
AIM: Electrospunning is a process that the charged polymer solution or melt jet efflux in the electrostatic field to prepare the 1Laboratory of
polymer nanofibers. This study aimed to prepare electrospun chitosan/collagen composite nanofibers and evaluate their cell Biomaterials and
Tissue Engineering,
biocompatibility. College of
METHODS: The experiment was carried out in the Laboratory of Biomaterials and Tissue Engineering, College of Chemistry, Chemistry, Chemical
Chemical Engineering and Biotechnology at Donghua University between November 2006 and October 2007. Taking Engineering and
hexafluoroisopropanol/trifluoroacetic acid as solvent, the composite nanofibers were prepared by electrospunning according to the Biotechnology, 2 State
Key Laboratory for
mass ratio of chitosan/collagen as 100:0, 80:20, 50:50, 20:80 and 0:100. The composite nanofibers were inoculated with porcine Modification of
iliac artery endothelial cells in vitro. The cell adhesion
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