83例医院感染败血症致病菌谱及耐药性分析.PDFVIP

5·70 · Chin J Nosocomiol Vol. 13 No. 6 2003 ·论 　著· 83 例医院感染败血症致病菌谱及耐药性分析 何卫平 , 王慧芬 (解放军第 302 医院 , 北京 100039) 摘要 : 目的 　研究医院感染败血症患者致病菌感染谱和耐药性的变化。方法 　用纸片扩散法对由医院感染败血 症患者分离的细菌进行药敏实验 ,并按 NCCL S 标准判断细菌耐药性。结果 　从 83 例医院感染败血症患者中分 离致病菌 103 株 , 以大肠埃希菌最多见,大部分分离菌对过去常用的抗菌药物有多重耐药性。结论 　细菌对常用 的抗菌药物产生了程度不同的耐药性 ,在临床使用抗菌药物时应特别注意耐药现象 ,并及时掌握细菌对抗菌药物 耐药的最新动态。 关键词 : 医院感染败血症 ; 细菌 ; 药物耐受性 中图分类号: R969. 3 　　文献标识码 : A 　　文章编号 : (2003) Pathogen Spectra and Their Drug Resistance Selected from 83 Patients with Septicemia due to Nosocomial Infection HE Weiping , WAN G Huifen ( The 302 nd Hospital of PL A , Beijin g 100039 , China) Abstract : OBJECTIVE To study the changes in pathogen spectra and drug resistance of bacteria selected from patients with septicemia due to nosocomial infection. METHODS Diffusion tests were used to measure the antibiotic sensitivity of bacteria isolated from the patients with septicemia due to nosocomial infection , and resistance was analysed according to NCCL S standard. RESULTS A total of 103 isolates were collected from 83 these cases , the majorit y is Escherichia coli , the multiple drug resistance was seen in the most isolates to the commonly used antibiotics. CONCL USIONS The resistance of bacteria to the commonly used antibiotics was produced in various degrees. Bacteria resistance should be emphasised during clinical therap y with antibiotics , and the resistance trends of isolates should be followed in time. Key words : Septicemia due to nosocomial infected ; Bacteria ; Drug resistance 　　医院感染败血症是一种较为严重的临床疾患 , 生长的“7C”和高渗培养基中 ,通过制动血液培养仪 常并发于有严重基础疾病患者而危及