培元通脑胶囊治疗脑卒中后假性球麻痹40例.docVIP

培元通脑胶囊治疗脑卒中后假性球麻痹40例【摘要】 目的 观察培元通脑胶囊治疗脑卒中后假性球麻痹的疗效。方法 将符合纳入标准的80例患者随机分为两组：治疗组40例，在西医常规对症治疗的同时加用培元通脑胶囊，3粒/次，3次/日，口服；对照组40例，按西医常规对症治疗，疗程30 d，治疗结束后评价疗效，比较两组有效率。结果 两组经治疗后，患者的症状均得到了明显的改善，但治疗组总有效率明显高于对照组。结论 培元通脑胶囊治疗脑卒中假性球麻痹疗效显著。? 【关键词】 培元通脑胶囊； 脑卒中假性球麻痹； 中医药治疗?? Effect of Pei-yuan through the brain capsule in treatment of pseudobulbar palsy after stroke ?LI Yan-mei,WANG Xin-zhi,ZHANG Hui-yong.The First Hospital Affiliated to Henan University of Traditional Chinese Medicine,Zhengzhou 450000,China?? 【Abstract】 Objective To observe the effect of Pei-Yuan through the brain capsule in treatment of pseudobulbar palsy after stroke.Methods 80 patients who meet the inclusion criteria were randomly divided into two groups,each group was 40 cases.Control group were treated by western medicine,on this basis treatment group were added by Peiyuan through the brain capsule,3 capsules per time,3/d.The efficacy was evaluated and compared after 30 days of treatment.Results After treatment,the symptoms were improved significantly in two groups, the total effective rate in the treatment group was significantly higher than that of the control group.Conclusion Pei-Yuan through the brain capsule is effective in the treatment of pseudobulbar palsy after stroke.? 【Key words】 Pei-yuan through the brain capsule; Pseudobulbar palsy after stroke; TCM ?? 假性球麻痹是脑血管病的常见症状和后遗症之一，是多次反复中风的必然结果，以构音障碍、吞咽困难、饮水即呛、舌体失柔及运动不灵、强哭强笑等为主要特征，严重影响患者的生活质量。笔者采用培元通脑胶囊治疗80例脑卒中假性球麻痹患者，取得了较好的疗效，现报道如下。? 1 资料与方法? 1.1 一般资料 80名患者均为2009年1月～2010年1月在河南中医学院第一附属医院脑病区住院的脑血管病患者，临床上均表现为不同程度的构音障碍、吞咽困难、饮水反呛等，其中男70例，女10例，年龄40～70岁，病程均＜15 d，随机分为治疗组和对照组。治疗组40例，其中脑梗死30例，脑出血10例；对照组40例，其中脑梗死36例，脑出血4例。两组在性别、年龄、病程及临床表现上经统计学处理差异均无统计学意义（?P?0.05），具有可比性。? 1.2 入选和排除标准 入选标准：（1）脑梗死病史。（2）症状：构音障碍和（或）吞咽困难、饮水呛咳。（3）体征：软腭反射及咽反射存在，舌肌运动困难，无舌肌萎缩。（4）影像学检查证实有延髓运动神经核以上部位的多灶梗死或出血病变［1］。排除标准：（1）临床上出现吞咽困难、饮水反呛等，但咽反射及软腭反射消失。（2）影像学证实延髓部位梗死灶或出血灶。（3）口腔、咽喉部局部病变。? 1.3 治疗方法 治疗组口服培元通脑胶囊，3粒/次，3次/d。方药组成：熟地、制首乌、鹿茸、全蝎、水蛭、地龙、肉桂、天冬、鳖甲、茯苓、赤芍、肉苁蓉、山楂、甘草，30 d