微波灭活建立兔股骨头坏死模型：最适宜灭活温度和作用时间的筛选.pdfVIP

中国组织工程研究与临床康复 第 j2眷 第2 2008—01—08出版 Journal ofClinical Rehabilitative Tmsue Engineering Research January＆2008 Vo1．12，No．2 Developing a rabbit model of the femoral head osteonecrosis induced by microwave heating：Optimum temperature and time screening★★☆ Peng Wu．xun’Wang Lei ，Deng Jin’，Gong Yue-kun。Zhao Xue-ling。Li Yan-lin。Li Shi-he。 ， ， ， ， ∞ 孵 诹 Abstract ’Department of BACKGRoUND：An ideal model of osteonecrosis of the femoral head is beneficial to the study on the cause of disease， Emergency and pathogenesy and treatment．So far there has not been a coherent method to prepare this mode1． Trauma． A衔liated Hospiml of Guiyang oBJECTIVE：TO establish a rabbit model of osteonecrosis of femoral head induced by microwave heating，and to decide Medica1 College， optimum microwave temperature and heating time． Guiyang 550004， Guizhou Province， DESIGN：Randomized controlled animal tria1． China； Disease SETTING：An imal Experimental Center of Kumning Medical College． Prevention and Control Center of MATERlALS：The experiment was performed at the Animal Experimental Center of Kunming Medical College between Guizhou Province， September 2004 and November 2005．Forty—eight healthy adult New Zealand rabbi~，either male or female，were provided by Guiyang 55Oo08． the Animal Experimental Center of Kumning Medical College．The animal procedure was accorde