administration of pde4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation管理pde4抑制剂抑制pannus-like炎症的抑制细胞因子的生产由巨噬细胞和滑膜成纤维细胞增殖.pdfVIP

Hindawi Publishing Corporation Mediators of Inflammation Volume 2007, Article ID 58901, 9 pages doi:10.1155/2007/58901 Research Article Administration of PDE4 Inhibitors Suppressed the Pannus-Like Inflammation by Inhibition of Cytokine Production by Macrophages and Synovial Fibroblast Proliferation Katsuya Kobayashi, Toshio Suda, Haruhiko Manabe, and Ichiro Miki Pharmacological Research Laboratories, Pharmaceutical Research Center, Kyowa Hakko Kogyo Co., Ltd., 1188 Shimotogari, Nagaizumi-Cho, Sunto-Gun, Shizuoka-Ken 411-8731, Japan Correspo