原创力文档breast cancer biology the multifaceted roles of mesenchymal stem cells乳腺癌生物学间充质干细胞的多方面的角色.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
breast cancer biology the multifaceted roles of mesenchymal stem cells乳腺癌生物学间充质干细胞的多方面的角色
Hindawi Publishing Corporation
Journal of Oncology
Volume 2008, Article ID 425895, 7 pages
doi:10.1155/2008/425895
Review Article
Breast Cancer Biology: The Multifaceted Roles of
Mesenchymal Stem Cells
Shyam A. Patel,1, 2 Andrew C. Heinrich,2 Bobby Y. Reddy,2 Balaji Srinivas,2
Nicole Heidaran,2 and Pranela Rameshwar2
1 Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
2 Division of Hematology and Oncology, Department of Medicine, New Jersey Medical School, University of Medicine and
Dentistry of New Jersey, Newark, NJ 07103, USA
Correspondence should be addressed to Pranela Rameshwar, rameshwa@
Received 23 July 2008; Accepted 8 October 2008
Recommended by Massimo Aglietta
Recent upsurge in the interest of breast cancer metastasis is partly attributed to the discovery of novel, yet unclear, mechanisms of
breast cancer interaction with sites of distant metastasis such as the bone marrow microenvironment. In this review, we discuss the
significance of the interactions between breast cancer cells and cells of the bone marrow. This is a subject of intense research studies
aim to provide new methods of treatments and perhaps the identification of new drug targets. This review also discusses the role
of inflammation and the bimodal function of the transforming growth factor-β signaling pathway in the process of tumorigenesis.
We bring attention to future prospects in breast cancer research, including the role of microRNAs in cancer quiescence in the
bone marrow and the application of microRNAs to basic science discoveries in oncology. Finally, we discuss the cancer stem cell
hypothesis, which is not a new idea, but has resurged with investigative questions.
Copyright © 2008 Shyam A. Patel et al. This i
您可能关注的文档
- biomarkers of acute kidney injury急性肾损伤的生物标志物.pdf
- biomarkers in nile tilapia oreochromis niloticus niloticus (linnaeus, 1758) to assess the impacts of river nile pollution bioaccumulation, biochemical and tissues biomarkers英文论文.pdf
- biological communication behavior through information technology implementation in learning accelerated生物通过信息技术实现通信行为学习加速.pdf
- biomass production and distribution in seedlings of coffea arabica genotypes under contrasting nursery environments in southwestern ethiopia幼苗的生物量生产和分配coffea阿拉比卡对比埃塞俄比亚西南部托儿所环境下基因型.pdf
- biomedical informatics and granularity生物医学信息学和粒度.pdf
- biomechanical prediction of abdominal aortic aneurysm rupture risk sensitivity analysis生物力学预测腹主动脉瘤破裂风险敏感性分析.pdf
- biomarkers of oxidative stress and personalized treatment of pulmonary tuberculosis emerging role of gamma-glutamyltransferase生物标记物的氧化应激和个性化治疗肺结核的新兴gamma-glutamyltransferase的角色.pdf
- biomass and productivity in sal and miscellaneous forests of satpura plateau (madhya pradesh) india森林生物量和生产力在萨尔和杂项satpura高原(中央邦)印度.pdf
- biomedical perspectives about women with chronic pelvic pain a qualitative analysis生物医学的角度对女性慢性骨盆疼痛定性分析.pdf
- biomass, carbon and nitrogen distribution in living woody plant parts of robinia pseudoacacia l. growing on reclamation sites in the mining region of lower lusatia (northeast germany)生物量、碳和氮的分布及以生活木本植物部分刺槐生长在回收站点矿业地区较低的卢萨蒂亚东北(德国).pdf
- breaking the symmetry of a circular system of coupled harmonic oscillators打破了对称耦合谐振子的循环系统.pdf
- breast surgery with application of doughnut mastopexy lumpectomy technique乳房手术应用的甜甜圈乳房固定术乳房肿瘤切除术技术.pdf
- breast implants for graduation a sociological examination of daughter and mother narratives隆胸的毕业考试社会学的女儿和母亲的叙述.pdf
- brand relationships a personality-based approach品牌关系人格本位的方法.pdf
- breast self examination practices among female secondary school teachers in a rural community in oyo state, nigeria乳房自我检查实践中学女教师中一个农村社区在欧州,尼日利亚.pdf
- breast tumor simulation and parameters estimation using evolutionary algorithms乳腺肿瘤使用进化算法仿真和参数估计.pdf
- brief review management of lupus nephritis–randomized controlled trials an update简单回顾狼疮nephritis-randomized对照试验一个更新的管理.pdf
- breast cancer stem cells survive periods of farnesyl-transferase inhibitor-induced dormancy by undergoing autophagy乳腺癌干细胞生存期farnesyl-transferase inhibitor-induced休眠发生自噬.pdf
- bregman distances, totally convex functions, and a method for solving operator equations in banach spaces师的距离,完全凸函数,解算子方程的一种方法,在巴拿赫空间.pdf
- bright light treatment of depression for 28 adolescents强光治疗青少年抑郁症的28.pdf
文档评论（0）