carbon dioxide insufflation in colonoscopy is safe a prospective trial of 347 patients二氧化碳注入技术在结肠镜检查是安全的一个前瞻性试验的347名患者.pdfVIP

Hindawi Publishing Corporation Diagnostic and Therapeutic Endoscopy Volume 2012, Article ID 692532, 4 pages doi:10.1155/2012/692532 Clinical Study Carbon Dioxide Insufflation in Colonoscopy Is Safe: A Prospective Trial of 347 Patients M. Geyer,1 U. Guller,2, 3 and Ch. Beglinger4 1 Gastroenterologie Wettingen, Rosengartenstrasse 2, 5430 Wettingen, Switzerland 2 Department of Oncology, Kantonsspital, 9007 St. Gallen, Switzerland 3 Department of Visceral Surgery and Medicine, University Hospital Bern, 3010 Bern, Switzerland 4 Department of Gastroenterology, University Hospital, 4031 Basel, Switzerland Correspondence should be addressed to M. Geyer, geyer@gastroenterologie-wettingen.ch Received 1 June 2012; Revised 16 August 2012; Accepted 29 August 2012 Academic Editor: Jean-Marc Dumonceau Copyright © 2012 M. Geyer et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Available evidence suggests that the use of CO2 insufflation in endoscopy is more comfortable for the patient. The safety of CO2 use in colonoscopy remains contentious, particularly in sedated patients. The objective of the present prospective trial was to assess the safety of CO2 colonoscopies. Methods. 109 patients from our previous randomized CO2 colonoscopy study and an additional 238 subsequent consecutive unselected patients who had a routine colonoscopy performed in a private practice were enrolled from April 2008 through September 2008. All but 2 patients were sedated. All patients were routinely monitored with transcutaneous CO2 measurement. Volumes of CO2 administered were correlated with capnographi