characterization of ppcp1 plasmids in yersinia pestis strains isolated from the former soviet union表征ppcp1鼠疫杆菌质粒的菌株孤立的来自前苏联.pdfVIP

Hindawi Publishing Corporation International Journal of Microbiology Volume 2010, Article ID 760819, 9 pages doi:10.1155/2010/760819 Research Article Characterization of pPCP1 Plasmids in Yersinia pestis Strains Isolated from the Former Soviet Union Chythanya Rajanna,1 Tamara Revazishvili,1 Mohammed H. Rashid,1 Svetlana Chubinidze,2, 3 Lela Bakanidze,2 Shota Tsanava,2, 3 Paata Imnadze,2, 3 Kimberly A. Bishop-Lilly,4 Shanmuga Sozhamannan,4 Henry S. Gibbons,5 J. Glenn Morris Jr.,1 and Alexander Sulakvelidze1 1 Emerging Pathogens Institute and Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, FL 32610, USA 2 National Center for Disease Control and Public Health, Georgian Ministry of Health, 0177 Tbilisi, Georgia 3 Tbilisi State University, 0218 Tbilisi, Georgia 4 Naval Medical Center Annex, Rockville, MD 20852, USA 5 US Army Edgewood Chemical Biological Center, Aberdeen Proving Ground, MD 21010, USA Correspondence should be addressed to Chythanya Rajanna, crajanna@epi.ufl.edu Received 23 July 2010; Revised 26 October 2010; Accepted 15 November 2010 Academic Editor: Todd R. Callaway Copyright © 2010 Chythanya Rajanna et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Complete sequences of 9.5-kb pPCP1 plasmids in three Yersinia pestis strains from the former Soviet Union (FSU) were determined and compared with those of pPCP1 plasmids in three well-characterized, non-FSU Y. pestis strains (KIM, CO92, and 91001). Two of the FSU plasmids were from strains C2614 and C2944, isolated from plague foci in Russia, and one