瘢痕疙瘩不同分型皮损血流及血管状况检测.docVIP

瘢痕疙瘩不同分型皮损血流及血管状况检测[摘要]目的:探讨瘢痕疙瘩(K)不同分型皮损的血流及血管状况。方法:将5例K患者皮损分为浸润K、增生K(红)、增生K(紫)、增生K(白)及老化K五型,同部位同时进行超声及皮肤镜检查,并与4例正常对照皮肤进行比较。结果:浸润K、增生K(红)、增生K(紫)及增生K(白)瘢痕组织内呈相对或绝对缺血或缺动脉血状态,浅表血管或细小、或通行异常、或通行不畅;老化K组织内血流状况不一,浅表血管形态分布接近正常皮肤。结论:K皮损分型不同,其血流状态及浅部血管表现亦不同。 [关键词]瘢痕疙瘩;超声;皮肤镜 [中图分类号]R619+.6 [文献标识码]A [文章编号]1008-6455(2010)04-0542-04 Status of blood flow and blood vessel in different type of keloid ZHAO Qing-li, MENG Ru-song, LIU Shu-ping, YANG Qing-qi, CAI Rui-kang (Department of Dermatology, Air Force General Hospital of Chinese PLA, Beijing 100036,China) Abstract: Objective To explore the status of the blood flow and the blood vessel in different type of keloid.MethodsThe lesions from 5 patients with keloid were divided into infiltrating, proliferative(red), proliferative(violet), proliferative(white) and aged parts. At same part the blood flow and the blood vessel were detected simultaneously with ultrasound and demoscopy, which were compared with those of normal skins from 4 controls.ResultsBlood or arterial blood shortage was presented in the tissue of infiltrating, proliferative(red), proliferative(violet) and proliferative (white) parts of keloid; moreover the shape of superficial blood vessel was abnormal. In the tissue of aged part the blood flow was dissimilarity, the shape and the distribution of superficial blood vessel were nearly normal.ConclusionsThe status of blood flow and the manifestation of superficial blood vessel are different in the light of different parts of keloid. Keywords:keloid;ltrasound; demoscopy 瘢痕疙瘩(Keloid, K)发病机制不清。研究表明,组织中血流及血管状况影响着K的形成与转归;K部位不同,其组织内的血管状况亦不同。本研究采用超声及皮肤镜检查技术无创性地对K不同分型皮损同时进行血流测定及血管数目、分布、形态观察,以期了解活体状态下K发生、发展、稳定、退化阶段中组织内微循环的变化,为阐明K发病机制做进一步的探索。 1资料和方法 1.1 病例及正常对照:K患者5例,其中男2例,女3例,年龄21～45岁;正常对照4例,其中男2例,女2例,年龄25～45岁。所有患者均符合K诊断标准[1],未曾经过手术、放疗、激光、冷冻及局部加压治疗,无皮损处注射糖皮质类固醇激素史,1个月内未曾系统及局部应用与治疗本病有关的药物。K患者及正常对照均无血液循环系统疾病史,2天内未曾饮入酒精及含乙醇的药物。 1.2 研究方法 1.2.1 受检皮损及皮肤的选择:将K患者皮损分型为浸润K、增生K(红)、增生K(紫)、增生K(白)、老化K五型(见表1)