cost-effectiveness of somatostatin analogues for the treatment of acromegaly in colombia生长抑素类似物治疗的成本效益在哥伦比亚肢端肥大症.pdfVIP

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cost-effectiveness of somatostatin analogues for the treatment of acromegaly in colombia生长抑素类似物治疗的成本效益在哥伦比亚肢端肥大症.pdf

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cost-effectiveness of somatostatin analogues for the treatment of acromegaly in colombia生长抑素类似物治疗的成本效益在哥伦比亚肢端肥大症

Open Journal of Endocrine and Metabolic Diseases, 2012, 2, 102-106 /10.4236/ojemd.2012.24016 Published Online November 2012 (http://www.SciRP.org/journal/ojemd) Cost-Effectiveness of Somatostatin Analogues for the Treatment of Acromegaly in Colombia 1,2 2,3 4 Rafael Alfonso-Cristancho , Santiago Herran Diazgranados , Kariluz Maestre Martinez , Oscar David Diaz-Sotelo2 1Pharmaceutical Outcomes Research and Policy Program, University of Washington, Seattle, USA 2RANDOM Foundation, Bogotá, Colombia 3Health Economics and Pharmacoeconomics Program, Pompeu Fabra University, Barcelona, Spain 4Novartis de Colombia, Rafael Alfonso, SA Email: ralfonso@ Received April 25, 2012; revised May 27, 2012; accepted June 28, 2012 ABSTRACT Background: Somatostatin analogues have shown to be effective in controlling the levels of growth hormone and are recommended for the treatment of acromegaly. These treatments have high costs of acquisition and their use might be restricted in limited resource settings. Objective: To evaluate the cost-effectiveness of somatostatin analogues for ac- romegaly in Colombia. Setting/Subjects/Intervention: A decision model was developed using a hypothetical cohort of patients with Acromegaly. Patients were treated according to the clinical practice of the country. Response to treatment and transition probabilities were derived from published literature. Costs and resource utilization were extracted from public and private sources in Colombia. Main Outcome Measure(s): Cos