哮喘患儿临床发病情况与肺炎支原体衣原体感染的相关性研究.docVIP

哮喘患儿临床发病情况与肺炎支原体、衣原体感染的相关性研究 [摘要]目的：探讨哮喘患儿临床发病情况与肺炎支原体（MP）、衣原体（CP）感染的相关性。方法：回顾性总结哮喘患儿90例临床资料设为观察组，根据一般资料类似原则搜集同期健康体检儿童40例资料设为对照组。所有130例资料均通过酶联免疫法检测体内CP-lgM、MP-lgM和CP-lgG水平并通过统计学方法进行比较，另外探讨哮喘发病病程与MP、CP感染的关系。结果：观察组患儿体内CP-lgM阳性者20例（22.2%），CP-lgG阳性者18例（20%），MP-lgM阳性者10例（11.1%）,明显高于对照组健康儿童感染情况（P0.05）；另外，病程3月的患儿CP感染率明显增大，患儿平均年龄与CP感染的persen相关系数为0.30（P0.05），表现弱相关性。结论：部分哮喘患儿的发病与CP感染密切相关，年龄较低的患儿因抗感染能力较低，更应重视对CP的预防。 [关键词]哮喘患儿，肺炎支原体，衣原体感染，相关性 Asthma in children with mycoplasma pneumonia, the clinical study on the relationship between Chlamydia infection [Abstract] Objective: To investigate the clinical incidence of asthma in children with mycoplasma pneumonia (MP), Chlamydia trachomatis (CP) infection. Methods: analysising clinical data of 90 children cases with asthma for the observation group, according to the general principle of similar data collected the data of 40 cases of healthy children as control group. All 130 cases were by enzyme-linked immunosorbent assay in CP-lgM, MP-lgM and CP-lgG levels and by statistical method, and to investigate the relationship between asthma and MP, CP infection disease. Results: the observation group in the patients of CP-lgM were positive in 20 cases (22.2%), 18 cases of CP-lgG positive (20%), 10 cases of MP-lgM positive (11.1%), significantly higher than that of the control group (P0.05 infection in healthy children); in addition, the course of 3 months of children with CP infection rate increased significantly, persen correlation coefficient Huan Erping age and CP infection was 0.30 (P0.05), showed weak correlation. Conclusion: children with asthma are closely related to the pathogenesis of CP infection and age, the lower the children for the anti infection ability is low, more attention should be paid to the prevention of CP. [keyword] children with asthma, pneumonia mycoplasma, chlamydia infection, correlation 儿童哮喘在儿科临床上属于常见的呼吸系统疾病之一，近年来儿童哮喘的患病率和死亡率均有上升趋势，发病后的患儿身心健康受到严重影响，而CP与MP是导致患儿发病的重要原因（相关文献[1-2]证明：小儿哮喘的发病与CP、MP的感染有关），为了探讨哮喘患儿临床