a study of [au(ethylenediamine)cl2]cl interaction with l-methionine and dl-seleno-methionine by 1h and 13c nmr spectroscopy的研究[cl2盟(乙二胺)]cl与l-methionine互动和dl-seleno-methionine 1 h和13 c核磁共振光谱学.pdfVIP

下载本文档

7
0
约2.71万字
约 10页
2017-08-29 发布于上海
举报
版权申诉

a study of [au(ethylenediamine)cl2]cl interaction with l-methionine and dl-seleno-methionine by 1h and 13c nmr spectroscopy的研究[cl2盟(乙二胺)]cl与l-methionine互动和dl-seleno-methionine 1 h和13 c核磁共振光谱学.pdf

1、本文档共10页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

a study of [au(ethylenediamine)cl2]cl interaction with l-methionine and dl-seleno-methionine by 1h and 13c nmr spectroscopy的研究[cl2盟(乙二胺)]cl与l-methionine互动和dl-seleno-methionine 1 h和13 c核磁共振光谱学

Spectroscopy 24 (2010) 567–575 567 DOI 10.3233/SPE-2010-0478 IOS Press A study of [Au(ethylenediamine)Cl ]Cl 2 interaction with L-methionine and DL-seleno-methionine by 1H and 13C NMR spectroscopy Bassem A. Al-Maythalony a , Mohamed I.M. Wazeer a , Anvarhusein A. Isab a,∗ and Saeed Ahmad b a Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia b Department of Chemistry, University of Engineering and Technology, Lahore, Pakistan Abstract. The interaction of [Au(en)Cl ]Cl with L-methionine (Met) and DL-seleno-methionine (Se-Met) was carried out in 2 13 D2 O solution at ∼pH 3.8. C NMR spectra were interpreted by comparison with the spectra recorded after the reaction of Met or Se-Met with HAuCl and also after oxidation by H O . Reactions of [Au(en)Cl ]Cl with Met and Se-Met were found to 4 2 2 2 proceed through the exchange of chloride ligands from complex with Met or Se-Met. Gold(III) reduction takes place during the reaction and en ligand was released from [Au(en)Cl2 ]Cl complex. Keywords: L-methionine, DL-seleno-methionine, NMR spectroscopy Abbreviations en: Ethylenediamine Met: L-methionine Met–SO–CH3 : L-methionine sulphoxide Se-Met: DL-seleno-methionine Met–SeO–CH3 : DL-methionine-seleno-oxide 1. Introduction Gold complexes have been studied extensively as antiarthritic and anticancer agents during the last four decades [1–13]. Auranoﬁn and Myocrisin are some examples of gold(I) drugs that have been used for the treatment of rheumatoid arthritis [7,13]. Gold(III) complexes, which are iso-electronic