a woman with a lower lip nodule what is your diagnosis一个女人嘴唇结节较低你的诊断.pdfVIP

SAGE-Hindawi Access to Research Pathology Research International Volume 2011, Article ID 656394, 4 pages doi:10.4061/2011/656394 Case Report A Woman with a Lower Lip Nodule: What Is Your Diagnosis? Deba P. Sarma,1 Mingui Chen,1 Todd Stevens,1 Daniel Albertson,1 Spencer Rusin,1 and Stephanie Ortman2 1 Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA 2 Department of Dermatology, Creighton University Medical Center, Omaha, NE 68131, USA Correspondence should be addressed to Deba P. Sarma, dpsarma@ Received 23 December 2010; Accepted 22 February 2011 Academic Editor: Allen Burke Copyright © 2011 Deba P. Sarma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Angiolymphoid hyperplasia with eosinophilia (ALHE), also known as epitheliod hemangioma is an uncommon benign vascular tumor of the skin. It usually presents as nodules and erythema over the ears, forehead, or scalp. Histologically, the lesion is composed of a combination of immature blood vessels, endothelial cells with distinct epitheliod appearance and chronic inflammatory cell infiltration with numerous eosinophils. Such a case occurring on the lower lip of a 55-year-old woman is presented. The lesion was completely excised with clear margins. Surgical resection is the preferred mode of treatment and is curative. 1. Case Synopsis marker CD31 (Figure 5), but negative for epithelial marker CK AE1/3 and neuronal marker S-100. The peripheral A