an efficient preparation, spectroscopic properties, and crystal structure of 1,1-bis(4-[2-(dimethylamino)ethoxy]phenyl)-2-(3-guaiazulenyl)ethylene一种有效的制备、光谱性质和晶体结构的一号乙(4 -(2 -(二甲胺基)乙氧基)苯基)2 -乙烯(3-guaiazulenyl).pdfVIP

Hindawi Publishing Corporation Research Letters in Organic Chemistry Volume 2009, Article ID 684359, 5 pages doi:10.1155/2009/684359 Research Letter An Efficient Preparation, Spectroscopic Properties, and Crystal Structure of 1,1-Bis(4-[2-(dimethylamino)ethoxy]phenyl)-2-(3- guaiazulenyl)ethylene Shin-ichi Takekuma,1 Seiki Hori,1 Toshie Minematsu,2 and Hideko Takekuma1 1 Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, 3-4-1 Kowakae, Higashi-Osaka-shi, Osaka 577-8502, Japan 2 School of Pharmaceutical Sciences, Kinki University, 3-4-1 Kowakae, Higashi-Osaka-shi, Osaka 577-8502, Japan Correspondence should be addressed to Shin-ichi Takekuma, takekuma@apch.kindai.ac.jp Received 24 November 2008; Accepted 20 February 2009 Recommended by William Ogilvie Reaction of 2-(3-guaiazulenyl)-1,1-bis(4-hydroxyphenyl)ethylene with 2-chloroethyldimethylammonium chloride in acetone in the presence of K2 CO3 at reflux temperature for 24 hours gives a new title compound in 89% yield. Spectroscopic properties and crystal structure of the target molecule are reported. Copyright © 2009 Shin-ichi Takekuma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 1. Introduction in 97% yield [7]. Similarly, the reaction of guaiazulene with 1,2-bis(4-hydroxyphenyl)-1,2-ethanediol under the It is well known that chlorotrianisene [2-chloro-1,1,2-tris(4- same reaction conditions as the above afforded 2-(3- methoxyphenyl)ethylene] (1) [1] exhibit