risk factors of anastomotic thrombosis in 200 head and neck free flaps among asian patients200年吻合口血栓形成风险因素头部和颈部自由皮瓣在亚洲病人.pdf

Surgical Science, 2012, 3, 237-241 /10.4236/ss.2012.35046 Published Online May 2012 (http://www.SciRP.org/journal/ss) Risk Factors of Anastomotic Thrombosis in 200 Head and Neck Free Flaps among Asian Patients 1 1 2 3 Takaya Makiguchi , Kazunobu Hashikawa , Daisuke Sugiyama , Satoshi Yokoo , Hiroto Terashi1 4 2 1 , Kenichi Nibu , Shunichi Kumagai , Shinya Tahara 1Department of Plastic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan 2 Department of Evidence Based Laboratory Medicine, Kobe University Graduate School of Medicine, Kobe, Japan 3Department of Stomatology and Oral Surgery, Gunma University Graduate School of Medicine, Gunma, Japan 4Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan Email: takayamakiguchi@ Received February 6, 2012; revised April 15, 2012; accepted April 27, 2012 ABSTRACT Background: Despite excellent results from free flap transfers, postoperative thrombosis does occur and, although in- frequent, causes total loss of the flap. We investigate the risk factors of anastomotic thrombosis in head and neck free flaps. Study Design, Subjects and Methods: A retrospective analysis was carried out on 200 consecutive free flaps applied to patients who underwent head and neck reconstruction. Multiple logistic regression analysis was conducted to identify risk factors of anastomotic thrombosis, taking into account twelve factors: diabetes, obesity, hypertension, hy- pertriglyceridemia, proteinuria, age, gender, smoking habit, hab