role of bmi in the association of the tcf7l2 rs7903146 variant with coronary heart disease the atherosclerosis risk in communities (aric) studybmi在协会的tcf7l2 rs7903146变体与冠心病动脉粥样硬化风险在社区(aric)研究.pdf

Hindawi Publishing Corporation Journal of Obesity Volume 2010, Article ID 651903, 5 pages doi:10.1155/2010/651903 Research Article Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study Anna M. Kucharska-Newton,1 Keri L. Monda,1 Suzette J. Bielinski,2 Eric Boerwinkle,3 Thomas D. Rea,4 Wayne D. Rosamond,1 James S. Pankow,5 ¨ 6 1 1 Anna Kottgen, Gerardo Heiss, and Kari E. North 1 Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA 2 Division of Epidemiology, Department of Health Services Research, Mayo Clinic, Rochester, MN 55905, USA 3 Human Genetics Center and Division of Epidemiology, University of Texas, Houston, TX 77225, USA 4 Department of Medicine, University of Washington, Seattle, WA 98195, USA 5 Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA 6 Department of Epidemiology, Johns Hopkins University, Baltimore, MD 21205, USA Correspondence should be addressed to Anna M. Kucharska-Newton, anna newton@ Received 29 June 2009; Revised 10 December 2009; Accepted 14 January 2010 Academic Editor: Gianluca Iacobellis Copyright © 2010 Anna M. Kucharska-Newton et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We examined the association of variation in the type 2 diabetes risk-conferring TCF7L2 gene with the risk of incident coronary heart disease