sex differences associated with primary biliary cirrhosis性别差异与原发性胆汁性肝硬化.pdf

Hindawi Publishing Corporation Clinical and Developmental Immunology Volume 2012, Article ID 610504, 11 pages doi:10.1155/2012/610504 Review Article Sex Differences Associated with Primary Biliary Cirrhosis Daniel S. Smyk,1 Eirini I. Rigopoulou,2 Albert Pares,3 Charalambos Billinis,4 Andrew K. Burroughs,5 Luigi Muratori,6 Pietro Invernizzi,7, 8 and Dimitrios P. Bogdanos1, 2, 9 1 Institute of Liver Studies, King’s College London School of Medicine, Denmark Hill Campus, London SE59PJ, UK 2 Department of Medicine, University of Thessaly Medical School, Viopolis, 41110 Larissa, Greece 3 Liver Unit, CIBEREHD, IDIBAPS, Hospital Clinic University of Barcelona, 08036 Barcelona, Spain 4 Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece 5 The Sheila Sherlock Liver Centre, and University Department of Surgery, Royal Free Hospital, London NW32QG, UK 6 Department of Clinical Medicine, Alma Mater Studiorum, Universita di Bologna, Policlinico Sant’Orsola-Malpighi, ` 40138 Bologna, Italy 7 Center for Autoimmune Liver Diseases, Division of Internal Medicine, IRCCS Istituto Clinico Humanitas, 20089 Rozzano, Italy 8 Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, CA 95616, USA 9 Department of Cellular Immunotherapy and Molecular Immunodiagnostics, Institute for Biomedical Research Technology, 41222 Larissa, Greece Correspondence should be addressed to Dimitrios P. Bogdanos, dimitrios.bogdanos@kcl.ac.uk Received 27 January 2012; Accepted 27 February 2012 Academic Editor: T. Nakayama Copyright © 2012 Daniel S. Smyk et al. This is an open