a higher number of tms-elicited mep from a combined hotspot improves intra- and inter-session reliability of the upper limb muscles in healthy individuals更多的tms-elicited议员从热点相结合提高内部和inter-session上肢肌肉的健康个体的可靠性.pdfVIP

a higher number of tms-elicited mep from a combined hotspot improves intra- and inter-session reliability of the upper limb muscles in healthy individuals更多的tms-elicited议员从热点相结合提高内部和inter-session上肢肌肉的健康个体的可靠性.pdf

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a higher number of tms-elicited mep from a combined hotspot improves intra- and inter-session reliability of the upper limb muscles in healthy individuals更多的tms-elicited议员从热点相结合提高内部和inter-session上肢肌肉的健康个体的可靠性

A Higher Number of TMS-Elicited MEP from a Combined Hotspot Improves Intra- and Inter-Session Reliability of the Upper Limb Muscles in Healthy Individuals Andisheh Bastani*, Shapour Jaberzadeh Department of Physiotherapy, School of Primary Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia Abstract We aimed to determine, using transcranial magnetic stimulation (TMS), the number of elicited motor evoked potentials (MEPs) that induces the highest intra- and inter-sessions reliability for the extensor carpi radialis (ECR) and first dorsal interosseus (FDI) muscles. Twelve healthy subjects participated in this study on two separate days. Single pulse magnetic stimuli were triggered with Magstim 2002 to obtain MEPs from the muscles of interest, with the subjects in a relaxed position. Reliability of MEP responses was investigated in three blocks of 5, 10 and 15 trials. The intra- and inter-session reliability of the MEPs’ amplitudes and latencies were assessed using intraclass correlation coefficients (ICCs). Repeated measures ANOVA and paired t-tests revealed no significant time effect in the MEP amplitude and latency measurements (P.0.05). The ICCs indicated high intra-session reliability in the MEPs’ amplitudes for the ECR and FDI muscles (0.77 to 0.99, 0.90 to 0.99, respectively) and latency (0.80 to 1.00, 0.75 to 0.97, respectively). The MEPs’ amplitudes also had high inter- session reliability (0.84 to 0.97, 0.88 to 0.93, respectively), as did their latency (0.80 to 0.90, 0.75 to 0.97, respectively). Highest intra- and inter-session reliability was achieved for blocks of 10 and 15 trials. Our data suggest that intra- and inter-session comparisons should be performed using at least 10 MEPs in ‘‘combined hotspot’’ stimulation technique to ensure highest

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