外源性补充硫酸亚铁对运动大鼠骨骼肌线粒体呼吸链酶活性及自由基代谢得影响.pdf

Abstract Mitochondria are the places provide energy movement in the mitochondria, within the way by oxidative phosphorylation of the energy stored energy material for chemical conversion (ATP), in order to meet the needs of the body. This study used to rat exogenous added ferrous sulfate with sports training for experimental model, using the physiology and biochemistry of the theory and method of rats, skeletal muscle enzyme activity and mitochondrial respiratory chain radicals metabolism indicators analyzed statistical research through the sports training and supplement of ferrous sulfate rats to the respiratory chain enzymes and free radicals metabolism, through the study, hope for the workers provide relevant theoretical basis. Method of experimental and object ： Five weeks Wistar rats 60 healthy male, weight, adaptability is 100 gold in two angels to feed animals ran machine room environment and the animals. Ran machine adaptive method: every day running platform for 0 degrees slope, ran machine speed increasing from 10m/min 12m/min, time to run for 10min Taiwan training. Experimental animals shall be divided into: quiet group (C, n = 10), in the exercise group (T,n = 10), small doses of iron in the exercise group (S，n =10 ), and in iron, and in the exercise group (M，n = 10), large doses of iron in the exercise group (L, n = 10). All week weigh weight a rat day, iron supplements by way of ferrous sulfate gastric lavage solution. The dose of iron: Small doses of iron group every day 28.85 mg/kg mouse and rat weight in each rat day iron group by 57.7 mg/kg weight, large doses of rats iron group 115.4 m/kg ，g per day by rat rat/kg weight. In the exercise group and iron + movement rats were increasing load ran machine