老年慢性心力衰竭患者甲状腺功能异常变化规律.docVIP

老年慢性心力衰竭患者甲状腺功能异常变化规律3 熊宝福1 1江西省抚州市第一人民医院老年科，江西抚州 344000；2江西省金溪县第三医院内科，江西金溪 344800； 3江西省中医药高等专科学校附属医院内科，江西抚州 344000 [摘要] 目的 探讨老年慢性心力衰竭（CHF）患者甲状腺功能异常的变化规律。 方法 对100例CHF患者抽取晨间肘静脉血，用放射免疫法测定FT3、FT4及TSH。 结果 老年人CHF甲状腺功能异常患病率39.56%（36/91），甲状腺功能减退（下文中简称：甲减）15.38%（14/91），亚临床甲减24.18%（22/91）；且甲状腺功能异常患病率与心衰病程呈正相关（P 0.001），与心功能程度呈负相关。 结论 对CHF患者常规进行甲状腺功能检测很有必要，可提高甲减性心脏病及CHF合并甲状腺功能异常的正确诊断。CHF合并甲减患者在常规抗心衰治疗基础上补充甲状腺素治疗可以改善心功能。 [关键词] 慢性心力衰竭；甲状腺功能减退；亚临床甲减 [中图分类号] R541.6 [文献标识码] B [文章编号] 1673—9701（2012）27—0156—03 The variation of abnormal thyroid function in elderly patients with chronic heart failure YU Yaoming1 XUN Yi2 LI Lan3 XIONG Baofu1 1. Department of Geriatrics，the First People’s Hospital of Fuzhou City in Jiangxi Province，Fuzhou 344000，China；2. Department of Internal Medicine，the Third Hospital of Jinxi County in Jiangxi Province，Jinxi 344800，China；3. Department of Internal Medicine，the Affiliated Hospital of Jiangxi Traditional Chinese Medicine College，Fuzhou 344000，China [Abstract] Objective To investigate the variation of abnormal thyroid function in elderly patients with chronic heart failure（CHF）. Methods FT3、FT4 and TSH were detected by radioimmunoassay from 100 patients with CHF in the morning. Results The prevalence of abnormal thyroid function in elderly patients with chronic heart failure（CHF）was 39.56%（36/91）， the prevalence of hypothyroidism in that patients was 15.38%（14/91）and the prevalence of subclinical hypothyroidism in that patients was 24.18%（22/91）. Furthermore， the correlation between the prevalence of abnormal thyroid function and the duration of heart failure was positive（P 0.001）， while the correlation between the prevalence of abnormal thyroid function and degree of cardiac function was negative. Conclusion It is necessary to do thyroid function examination in patients with chronic heart failure（CHF）. It could improve the correct diagnosis of hypothyroidism heart disease and the chronic heart failure combined with abnormal thyroid f