原创力文档characterization of a new vaccinia virus isolate reveals the c23l gene as a putative genetic marker for autochthonous group 1 brazilian vaccinia virus描述一个新的牛痘病毒隔离揭示了c23l基因作为一种公认的原地组1巴西牛痘病毒的遗传标记.pdfVIP
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characterization of a new vaccinia virus isolate reveals the c23l gene as a putative genetic marker for autochthonous group 1 brazilian vaccinia virus描述一个新的牛痘病毒隔离揭示了c23l基因作为一种公认的原地组1巴西牛痘病毒的遗传标记
Characterization of a New Vaccinia virus Isolate Reveals
the C23L Gene as a Putative Genetic Marker for
Autochthonous Group 1 Brazilian Vaccinia virus
1. 1. 1 1 1
Felipe L. Assis , Gabriel M. F. Almeida , Danilo B. Oliveira , Ana P. M. Franco-Luiz , Rafael K. Campos ,
2 ´ 1 1 ˆ 3 1
Maria I. M. Guedes , Flavio G. Fonseca , Giliane S. Trindade , Betania P. Drumond , Erna G. Kroon ,
ˆ ˜ 1*
Jonatas S. Abrahao
´
1 Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil, 2 Departamento de Medicina Veterinaria Preventiva,
Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil, 3 Departamento de Parasitologia, Microbiologia e Imunologia, Universidade Federal de Juiz de
Fora, Juiz de Fora, Minas Gerais, Brazil
Abstract
Since 1999, several Vaccinia virus (VACV) isolates, the etiological agents of bovine vaccinia (BV), have been frequently
isolated and characterized with various biological and molecular methods. The results from these approaches have grouped
these VACV isolates into two different clusters. This dichotomy has elicited debates surrounding the origin of the Brazilian
VACV and its epidemiological significance. To ascertain vital information to settle these debates, we and other research
groups have made efforts to identify molecular markers to discriminate VACV f
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