原创力文档chromogranin a (cga) as poor prognostic factor in patients with small cell carcinoma of the cervix results of a retrospective study of 293 patientschromogranin(cga)作为预后不良因素子宫颈小细胞癌患者的回顾性研究的293名患者的结果.pdfVIP
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chromogranin a (cga) as poor prognostic factor in patients with small cell carcinoma of the cervix results of a retrospective study of 293 patientschromogranin(cga)作为预后不良因素子宫颈小细胞癌患者的回顾性研究的293名患者的结果
Chromogranin A (CgA) as Poor Prognostic Factor in
Patients with Small Cell Carcinoma of the Cervix: Results
of a Retrospective Study of 293 Patients
1 1 2 3 1 1 1
Ling-Min Liao , Xin Zhang , Yu-Feng Ren , Xiao-Ying Sun , Na Di , Nan Zhou , Rui-Ke Pan , Shu-
4,5 1
Hua Ma *, Li-Xue Zhou *
1 Department of Gynecology and Obstetrics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China, 2 Department of Radiotherapy, First
Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China, 3 Department of Gynecology and Obstetrics, Feng Tian Hospital, Shenyang Medical College,
Shenyang, Liaoning, China, 4 Department of Radiology, First Affiliated Hospital, Medical College of Shantou University, Shantou, Guangdong, China, 5 Guangdong Key
Laboratory of Medical Molecular Imaging, Shantou, Guangdong, China
Abstract
Background: Small cell carcinoma of the cervix (SCCC) is a very rare tumor. Due to its rarity and the long time period, there
is a paucity of information pertaining to prognostic factors associated with survival. The objective of this study was to
determine whether clinicopathologic finings or immunohistochemical presence of molecular markers predictive of clinical
outcome in patients with SCCC.
Methodology and Findings: We retrospectively reviewed a total of 293 patients with SCCC (47 patients from Cancer Center
of Sun Yat-sen University in china, 71 patients from case report of china journal, 175 patients from case report in PubMed
database). Of those 293 patients with SCCC, the median survival time is 23 months. The 3-year overall survival rates (OS) and
3-year disease-free survival rates (DFS) for all patients were 34.5% and 31.1%, respectively. Univa
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