crest – classification resources for environmental sequence tags佳洁士u2014u2014分类资源环境序列标签.pdfVIP

CREST – Classification Resources for Environmental Sequence Tags ´ 1,2 1 3 4 2 Anders Lanzen *, Steffen L. Jørgensen , Daniel H. Huson , Markus Gorfer , Svenn Helge Grindhaug , 2,5 ˚ 1 6 Inge Jonassen , Lise Øvreas , Tim Urich * 1 Department of Biology and Centre for Geobiology, University of Bergen, Bergen, Norway, 2 Uni Computing, Uni Research AS, Bergen, Norway, 3 Centre for ¨ ¨ Bioinformatics, Tubingen University, Tubingen, Germany, 4 Fungal Genetics and Genomics Unit, AIT Gmbh and University of Natural Resources and Life Sciences, Tulln, Austria, 5 Department of Informatics, University of Bergen, Bergen, Norway, 6 Department of Genetics in Ecology, University of Vienna, Vienna, Austria Abstract Sequencing of taxonomic or phylogenetic markers is becoming a fast and efficient method for studying environmental microbial communities. This has resulted in a steadily growing collection of marker sequences, most notably of the small- subunit (SSU) ribosomal RNA gene, and an increased understanding of microbial phylogeny, diversity and community composition patterns. However, to utilize these large datasets together with new sequencing technologies, a reliable and flexible system for taxonomic classification is critical. We developed CREST (Classification Resources for Environmental Sequence Tags), a set of resources and tools for generating and utilizing custom taxonomies and