determinants of treatment adherence among smear-positive pulmonary tuberculosis patients in southern ethiopia痰检阳性肺结核患者治疗依从性的决定因素在埃塞俄比亚南部.pdfVIP

PLoS MEDICINE Determinants of Treatment Adherence Among Smear-Positive Pulmonary Tuberculosis Patients in Southern Ethiopia Estifanos Biru Shargie1,2[*, Bernt Lindtjørn1[ 1 Centre for International Health, University of Bergen, Bergen, Norway, 2 Southern Nations, Nationalities and Peoples’ Regional State Health Bureau, Awassa, Ethiopia Funding: The Centre for A B S T R A C T International Health, University of Bergen funded this study. The funders had no role in study design, data collection and analysis, decision Background to publish, or preparation of the manuscript. Defaulting from treatment remains a challenge for most tuberculosis control programmes. It may increase the risk of drug resistance, relapse, death, and prolonged infectiousness. The aim Competing Interests: The authors of this study was to determine factors predicting treatment adherence among smear-positive have declared that no competing interests exist. pulmonary tuberculosis patients. Academic Editor: Philip Hopewell, University of California San Methods and Findings Francisco, United States of America A cohort of smear-positive tuberculosis patients diagnosed and registered in Hossana Citation: Shargie EB, Lindtjørn B Hospital in southern Ethiopia from 1 September 2002 to 30 April 2004 were prospectively (2007) Determinants of treatment adherence among smear-positive included. Using a structured questionnaire, potential predictor factors for defaulting from pulmonary tuberculosis patients in treatment were recorded at the beg