direct infection and replication of naturally occurring hepatitis c virus genotypes 1, 2, 3 and 4 in normal human hepatocyte cultures直接感染和复制的天然丙型肝炎病毒基因型1、2、3和4在人类肝细胞正常的文化.pdfVIP

Direct Infection and Replication of Naturally Occurring Hepatitis C Virus Genotypes 1, 2, 3 and 4 in Normal Human Hepatocyte Cultures Martina Buck1,2* 1 Department of Medicine and Moores Cancer Center, University of California, La Jolla, California, United States of America, 2 Department of Medicine, VA Healthcare Center, San Diego, California, United States of America Abstract Background: Hepatitis C virus (HCV) infection afflicts about 170 million individuals worldwide. However, the HCV life cycle is only partially understood because it has not been possible to infect