diversity of hiv-1 subtype b implications to the origin of bf recombinants多样性的hiv - 1亚型b影响高炉重组的起源.pdfVIP

Diversity of HIV-1 Subtype B: Implications to the Origin of BF Recombinants ´ Elcio Leal*, Fabiola E. Villanova ´ ´ Federal University of Para, Belem, Brazil Abstract Background: The HIV-1 subtype B epidemic in Brazil is peculiar because of the high frequency of isolates having the GWGR tetramer at V3 loop region. It has been suggested that GWGR is a distinct variant and less pathogenic than other subtype B isolates. Methodology/Principal Findings: Ninety-four percent of the HIV-1 subtype B worldwide sequences (7689/8131) obta