dkk4 and eda regulate distinctive developmental mechanisms for subtypes of mouse hairdkk4和eda调节独特的发育机制亚型的老鼠的头发.pdfVIP

Dkk4 and Eda Regulate Distinctive Developmental Mechanisms for Subtypes of Mouse Hair Chang-Yi Cui, Makoto Kunisada, Yulan Piao, Victoria Childress, Minoru S. H. Ko, David Schlessinger* Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America Abstract The mouse hair coat comprises protective ‘‘primary’’ and thermo-regulatory ‘‘secondary’’ hairs. Primary hair formation is ectodysplasin (Eda) dependent, but it has been puzzling that Tabby (Eda-/y) mice still make secondary hair. We report