dlx5 is a cell autonomous regulator of chondrocyte hypertrophy in mice and functionally substitutes for dlx6 during endochondral ossificationdlx5是软骨细胞肥大细胞自动调节器在小鼠和功能在软骨内骨化dlx6替代品.pdfVIP

Dlx5 Is a Cell Autonomous Regulator of Chondrocyte Hypertrophy in Mice and Functionally Substitutes for Dlx6 during Endochondral Ossification Hui Zhu, Andrew J. Bendall* Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada Abstract The axial and appendicular skeleton of vertebrates develops by endochondral ossification, in which skeletogenic tissue is initially cartilaginous and the differentiation of chondrocytes via the hypertrophic pathway precedes the differentiation of osteoblasts and the deposition of a definitive bone m